Quantitative , genome - wide analysis of the DNA methylome in 1 sporadic pituitary adenomas
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چکیده
Conflict of Interest: 17 All authors declare that there is no conflict of interest that could be perceived as prejudicing the 18 impartiality of the research reported 19 Funding: This work was partially supported by the award of a research scholarship by the Vietnamese 20 Government to Cuong V Doung. 21 22 23 24 Page 1 of 29 Accepted Preprint first posted on 8 October 2012 as Manuscript ERC-12-0251
منابع مشابه
Quantitative, genome-wide analysis of the DNA methylome in sporadic pituitary adenomas.
DNA methylation is one of the several epigenetic modifications that together with genetic aberrations are hallmarks of tumorigenesis including those emanating from the pituitary gland. In this study, we examined DNA methylation across 27 578 CpG sites spanning more than 14 000 genes in the major pituitary adenoma subtypes. Genome-wide changes were first determined in a discovery cohort comprisi...
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تاریخ انتشار 2012